Unlike THC, CBD will not make you high. That said, this doesn’t mean CBD is not at all psychoactive, as many assert, says Jahan Marcu, PhD, director of experimental pharmacology and behavior at the International Research Center on Cannabis and Mental Health in New York City: “CBD does change cognition. It affects mood, which is why people take it for anxiety. And some find that it makes them more alert.”
But even though it's infiltrating pretty much every corner of the wellness world (hi, vegan CBD brownies!) many people still find CBD a little confusing—especially when it comes to figuring out the right way to use it and how to make sure the stuff you're buying is, you know, actually legit. Below, we asked experts to answer the most pressing questions about CBD.
CBD and THC interact with our bodies in a variety of ways. One of the main ways they impact us is by mimicking and augmenting the effects of the compounds in our bodies called “endogenous cannabinoids” - so named because of their similarity to the compounds found in the cannabis plant. These “endocannabinoids” are part of a regulatory system called the “endocannabinoid system”.
To make matters more confusing, nine states (including California, Washington, and Colorado) let residents buy cannabis-based products with or without THC. Nearly two dozen other “medical marijuana states” allow the sale of cannabis, including capsules, tinctures, and other items containing CBD or THC, at licensed dispensaries to people whose doctors have certified that they have an approved condition (the list varies by state but includes chronic pain, PTSD, cancer, autism, Crohn’s disease, and multiple sclerosis). Sixteen more states legalized CBD for certain diseases.
Tinctures – Typically tinctures are small glass or plastic “dropper” bottles that have cannabidiol oil mixed with a preserving solution such as alcohol. Tinctures were very a very common way to ingest botanical oils prior to the industrial revolution and are experiencing a resurgence in popularity as more people are looking for natural remedies. Tinctures with droppers allow you to put a few drops in your tea, under your tongue, or to bake the oil directly into your food. CLICK HERE to see our favorite tincture.
Unlike THC, CBD will not make you high. That said, this doesn’t mean CBD is not at all psychoactive, as many assert, says Jahan Marcu, PhD, director of experimental pharmacology and behavior at the International Research Center on Cannabis and Mental Health in New York City: “CBD does change cognition. It affects mood, which is why people take it for anxiety. And some find that it makes them more alert.”
Given CBD’s reputation as a popular, artisanal remedy, one would think that Epidiolex would command a lot of “off label” attention. After all, physicians often prescribe pharmaceuticals off label to treat conditions that were not the actual focus of clinical trials. But the costly price tag for Epidiolex (more than $30,000 annually) precludes off label prescribing as well as affordable access for tens of millions of Americans without health insurance.
There are many reputable brands on the market and American Shaman is certainly one of them. It’s understandably confusing because as you said, pretty much every company will say that theirs is the best. The approach that you are taking is very common…trying several different brands until you find the one that works best for you. It’s also great that you can take advantage of the assistance programs that many brands offer to help you reduce your cost. One final thing to note that is often overlooked by folks is the importance of finding your “sweet spot” serving size or dosage level. Contrary to what some people assume, the amount that you take for best results is different by individual. People tell us that they have the most success by starting low and increasing slowly as needed until they find that sweet spot. CBD oil also doesn’t work immediately for most people. It can take some time to build up and activate your endocannabinoid receptors so patience is also important. Best of luck to you on your CBD journey!
Canine consumers of CBD oil are well catered for by Green Garden Gold, which offers dog-friendly drops and peanut butter-flavored treats among its innovative range. Humans definitely haven’t been forgotten by this producer either, though, as they can take advantage of, for instance, its Panidiol Joint Formula, which is touted as a relief for nagging aches and pains. Alternatively, for any veteran CBD oil users looking for a particularly potent product, there’s the company’s Med Pac hemp oil supplement, the strongest variety of which contains a heavyweight 4,000 mg of CBD extract per bottle. And anybody wishing to be reassured of the quality of Green Garden Gold’s wares need only ask; yes, in the interests of transparency, the company is willing to hand over details of the results of third-party lab testing to anyone who puts in such a request.
The science behind CBD is in the relatively early stages. As a cannabinoid, we know that CBD interacts with receptors in your endocannabinoid system. The endocannabinoid system is integrated throughout your body — and this widespread, whole-body interaction creates a broad range of effects. Hence, the long list of possible benefits.   We may still be in the early stages of discovery, but there’s plenty of scientific studies and anecdotal evidence that CBD provides relief for an array of ailments. Here’s a non-exhaustive list of some potential benefits of CBD oil:
CBD, or canabidiol is an amazingly useful plant compound that is extracted from the cannabis plant. With volumes of medical science now at its back, this compound has been used effectively for a wide range of needs. These particularly wide-ranging applications are the result of its being a part of the “pleiotropic sedate” group. Compounds in this group are especially unique in their ability to affect and travel along many of the typically closed atomic pathways.
CBDOilUsers.com is not paid to include any brand in our list. We may, however, receive commissions from some of the companies if you make a purchase through links on this website. There are no additional costs for consumers and they support our work to educate and inform consumers so they can make the right buying and usage decisions for themselves.
Very much needed information! I’m a disabled Veteran with Anklyosing Spondelitis and related skelital/ muscle issues and CBD has been an off-limits product with the VA chronic pain clinics that dispense opiates… until recently with the addition of 0% THC – Thank you for the option!! (We actually have to sign a letter stating we will not use… else when we get tested at every appointment and THC is detected, we could be ejected from the pain clinic and our use of opiates for chronic pain!)

If you are discovering the benefits of CBD then our Pure CBD e-liquids may be the best place to start. Vaping is the recommended and one of the most effective method of consuming CBD as vaping facilitates absorption into the body. Our CBD vape liquid is produced for VSAVI in Europe in “Clean Room” laboratories. It is safe, natural, pure and free from both contaminates and THC.
What you gain from Full Spectrum CBD is called the “entourage effect.” Studies have suggested that CBD is most effective when it’s combined with other cannabinoids. Each cannabinoid has its own properties and confers its own benefits. Working together, a synergy is created that boosts the healing properties of CBD. Full spectrum CBD does, however, bring with it the sticky issue of THC. The government regulates concentration levels of THC at 0.3 percent, an amount which results in minimal psychoactivity.

First, a little background. Industrial hemp was legal in the United States until Congress passed the Marihuana Tax Act in 1937. ("Some of our early presidents grew hemp," notes Sarah Lee Gossett Parrish, a cannabis industry attorney based in Oklahoma.) Nearly 80 years later, the 2014 Farm Bill took the position that states can regulate the production of hemp and, as a result, CBD. Then last year, President Trump signed a new Farm Bill that made it federally legal to grow hemp.
Dr. Cohen has found that chronic conditions including autoimmune diseases and pain syndromes can be helped with a 6-mg under-the-tongue tincture (the fastest delivery system) or a 25-mg capsule taken twice a day. Dosages for topical products like lotions are especially hard to determine—there’s no clarity on how much CBD gets into the system through the skin.
Through its regularly updated and highly informative blog, Koi CBD goes the extra mile to help its customers learn about new developments in the field of CBD use. The company also helps its patrons out by publishing full lab results on each of its products, helping CBD oil users know exactly what to expect. And those purchases may include Koi’s bespoke full-spectrum CBD oil blend, complete with fellow cannabinoids CBDV, CBN and CBG – the inclusion of which, the company claims, “provide[s] the ultimate experience in CBD.” Also available to buy from Koi’s website are a range of 1,000 mg vaping liquids, lavender-scented body lotion, tropical-flavored gummies and, for canine CBD lovers, chewable treats.
CBD oil products generally have a shelf life of at least one year, if stored in a cool, dark place. Refrigeration is typically not necessary as long as it is kept somewhere where the temperature is less than 77 degrees Fahrenheit. Tinctures that use MCT coconut oil as the carrier oil are known to have a longer shelf life than those with hemp seed oil as the carrier oil.

Pioneers of the CBD industry, 4 Corners Cannabis helped pave the way for companies that want to provide quality products and utilize best practices. They grow their own strain of hemp and make small batches of true full-spectrum CBD products. Their prices place them lower down on our ranking, but their highly satisfied customers are more than willing to pay for the 4 Corners quality.  

Dispensaries: In states where marijuana is legal for recreational use, dispensaries are a common sight. They are much rarer in states with more restrictions. In states that permit the use of medical marijuana, hemp-based CBD oils do not normally require a prescription but marijuana-based oils do. Like brick-and-mortar locations, dispensaries offer more customer service. However, as noted, this may not be an option depending on the buyer’s state of residence. Also, CBD oil prices tend to be significantly higher at dispensaries.
Sadly, there are unscrupulous companies out there looking to take advantage of people wanting to try CBD oil. A free trial bottle of CBD oil sounds like a great deal. They say you just need to pay a small shipping and handling fee. But what really happens is that they will send you a very low quality product. They’ll also keep charging your credit card every month for as much as $90 per month until you cancel your “subscription” with them. This is an outright scam that you want to avoid.
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