Several weeks after a hysterectomy last spring, Bo Roth was suffering from exhaustion and pain that kept her on the couch much of the day. The 58-year-old Seattle speech coach didn’t want to take opioid pain-killers, but Tylenol wasn’t helping enough. Roth was intrigued when women in her online chat group enthused about a cannabis-derived oil called cannabidiol (CBD) that they said relieved pain without making them high. So Roth, who hadn’t smoked weed since college but lived in a state where cannabis was legal, walked into a dispensary and bought a CBD tincture.
You won’t have to worry about potency with Spruce CBD. That’s because the potency of Spruce’s CBD oils are verified by a third-party testing lab. Spruce carries both regular and high potency CBD oil formulations. Spruce’s regular potency CBD oil contains a moderate dose of 25 mg of CBD per serving while their max potency formulation packs a strong dose of 80 mg of CBD per serving.
The human body also produces cannabinoids, known as endocannabinoids, in a bodily system known as the endocannabinoid system (or ECS). The ECS promotes homeostasis by regulating a wide range of functions, including motor skills, mood, appetite, and sleep. As we age, our ECS produces fewer endocannabinoids; they may also decrease due to physical injury or disease. Replenishing depleted endocannabinoids with phytocannabinoids like CBD can help restore balance to the body.
The vast majority of CBD oils come in bottles measuring either 15 milliliters (mL), or 0.5 ounces; or 30 mL, or 1 ounce. However, CBD concentration is more important than bottle size. Concentration refers to the ratio of hemp oil solution (measured in mL) compared to the amount of CBD cannabinoid (measured in milligrams, or mg). A 15-mL bottle may contain 100 mg of CBD, 300 mg, 500 mg, or more. The higher the mg amount, the stronger the CBD oil will be. For this reason, the ‘mg’ measurement is also referred to as the oil’s strength; i.e., 400-mg oil might be called 400-strength oil.
Under federal law, cannabis (from which both CBD and marijuana are derived) is illegal everywhere, although the laws against it aren’t generally enforced in states that have legalized marijuana. Some manufacturers claim that CBD culled from legally imported industrial hemp, which has little to no THC, is fine to ship across the U.S., but many experts disagree, noting that because hemp comes from the same species as marijuana, cannabis sativa, all CBD falls under the DEA’s Schedule 1 designation. “This creative interpretation of the law runs afoul of reality,” says the Brookings Institution, a Washington, DC, think tank.
CBD Fx is another USA company that emphasizes the use of MCT oil for maximizing the bioavailability of the CBD compound to cells throughout the body. In layman’s terms, this basically means their goal is to create a highly efficient and effective tincture that bypasses metabolic breakdown processes in the digestive system. They’re also big into vape pens, CBD vaping and CBD concentrates (waxes, powders, crystal isolates etc), so they tend to appeal a lot to the younger population as well as older folks like me who need CBD oil basically just to get out of bed in the morning.    

The reason so many people are interested in cannabis products that don’t make them high, proponents say, is that CBD helps with everything from pain and nausea to rheumatoid arthritis, cancer, Crohn’s disease, and dementia. CBD is anti-inflammatory, anti-anxiety, antibacterial, immunosuppressive, and more, says Joseph Cohen, DO, a cannabis doctor in Boulder, CO.
Online Retailers: Most CBD oils are sold through online retailers. These establishments tend to have the widest product range, and many offer free doorstep delivery. Online retailers also frequently post product reviews, allowing buyers to compare different oils based on customer experiences to determine which is best for them. These reviews can also be used to evaluate the retailer based on customer service, delivery, and product quality.
cbdMD CBD oil contains simple ingredients—CBD-rich hemp extract, MCT oil from coconut, and natural flavors. It’s available in unflavored, berry, orange, or mint flavors. And cbdMD has the widest range of potencies we’ve found from 10 mg of CBD per serving all the way up to 250 mg of CBD per serving. Plus all U.S. orders get free shipping and are backed by a 30-day, money-back guarantee.
Dispensaries: In states where marijuana is legal for recreational use, dispensaries are a common sight. They are much rarer in states with more restrictions. In states that permit the use of medical marijuana, hemp-based CBD oils do not normally require a prescription but marijuana-based oils do. Like brick-and-mortar locations, dispensaries offer more customer service. However, as noted, this may not be an option depending on the buyer’s state of residence. Also, CBD oil prices tend to be significantly higher at dispensaries.

As Dixie Botanicals claims on its website, “When it comes to quality, we leave nothing to chance.” To that end, the company tests each CBD oil batch on no fewer than three occasions during the production process: once after the hemp oil it uses is extracted; then again upon the oil’s arrival in the U.S.; and, for the final time, after the substance has been put into its range of products. What’s more, Dixie Botanicals proves that such rigorous quality control doesn’t necessarily mean high price tags for customers: its 100 mg tincture drops, for example, come in at a reasonable $29.99 per 30 ml bottle. The company’s novel “Kicks,” meanwhile, combine chocolate, caffeine and CBD in handy bite-sized chews that may tempt coffee addicts and candy fiends alike.


Hemp Bombs is based in Tampa, Florida, and in addition to focusing on the purity and therapeutic effectiveness of their products, are dedicated to establishing themselves as a top brand in the industry with a specific target audience. One of our personal favorite products of theirs is the flavored CBD vape liquids, which are some of the best-tasting CBD vape juices we’ve ever had.
At the top of our ranking is Portland-based Lazarus Naturals, which has honed a reputation for high-quality, affordable CBD. Their consciously crafted CBD is sourced from organic, Oregon-grown hemp which the company controls from seed to sale. With low prices, a robust assistance program, free shipping, and a 30-day, no questions asked return policy, you really can’t go wrong with Lazarus Naturals.

If you are new to the world of CBD, it is definitely best for you to start with a lower dosage and work your way up from there. Some of the tinctures listed below have as few as 240mg of cannabidiol per bottle, while others are as high as 4850mg. While stronger isn’t always better, we appreciate those brands that have different options available to address different needs. Also, keep in mind that while a lower dose can give you more control over the amount you consume, a higher concentration is usually more cost effective. Higher concentrations will also contain more beneficial cannabinoids.
Vaporizers – Many state-licensed cannabis dispensaries offer high CBD strains of cannabis flower. This allows for reduced risk of paranoia while allowing for a high medicinal dose of CBD. Vaporizers are used to heat up the flower and remove the properties or compounds of the plant that you are looking for without combustion or smoking. Vaporizers use convection much like a convection oven. CLICK HERE to see our favorite vaporizer.
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