The human body also produces cannabinoids, known as endocannabinoids, in a bodily system known as the endocannabinoid system (or ECS). The ECS promotes homeostasis by regulating a wide range of functions, including motor skills, mood, appetite, and sleep. As we age, our ECS produces fewer endocannabinoids; they may also decrease due to physical injury or disease. Replenishing depleted endocannabinoids with phytocannabinoids like CBD can help restore balance to the body.
CBD Essence is another brand we’ve had plenty of experience with over the past 18 months or so, and my partner particularly likes his 600 mg Medicinal Grade tincture for quickly easing her anxiety. I haven’t tried them so much for may pain, but I do recall that a 30 mg dose was quite effective the last time I did take it. Also, the main reason they’re this high up on our list is because they’re a fair amount cheaper than Elixinol and PureKana. Their tinctures come in larger 2 oz bottles, but on a CBD-per-mg basis they’re about 20% less expensive than other top-quality brands.
Most human studies of CBD have been done on people who have seizures, and the FDA recently approved the first CBD-based drug, Epidiolex, for rare forms of epilepsy. Clinical trials for other conditions are promising, but tiny. In one Brazilian study published in 2011 of people with generalized social anxiety disorder, for example, taking a 600-mg dose of CBD (higher than a typical dose from a tincture) lessened discomfort more than a placebo, but only a dozen people were given the pill.
When it comes to CBD oil, NuLeaf Naturals is practically a veteran of the industry. Founded in 2014, this company has been offering simple, no-nonsense legal CBD for five years. NuLeaf uses specially bred therapeutic hemp plants that contain high levels of CBD and other beneficial cannabinoids like CBC, CBG, and CBN while maintaining low levels of the psychoactive cannabinoid THC.
Cost is another consideration. Most CBD oils are sold in concentrations of 300 to 750 mg, although this may range from less than 100 mg to more than 2,000. A good indicator of price-point is the cost per milligram. Low-cost CBD oils usually fall between five and 10 cents per mg; mid-range prices are 11 to 15 cents per mg; and higher-end oils cost 16 cents per mg or higher. Given these varying per-milligram costs, a bottle of CBD oil may be priced anywhere from $10 or less to $150 or more.
The main thing that is inherently clear when scouting out FabCBD (which is a super new brand by the way that only just got started this year), is that they’ve made a pretty serious effort to develop a modern lifestyle brand. If you take a look at their website, everything from the web design to the brand labeling to the text they use screams modern and hip.
The CBDistillery has two main strengths. The first is its variety of options. The CBDistillery offers CBD oil tinctures in a wide range of concentrations from 17mg up to 88 mg of CBD per serving. But what really sets the company apart is that they offer both full-spectrum and THC-free CBD oil options. Most people gravitate towards full-spectrum CBD oil to take advantage of the entourage effect. But with THC-free CBD oil, you can enjoy the benefits and effects of CBD even if you’re subject to mandatory drug testing.
It’s fair to say that the CBD market is thriving. According to market intelligence company Hemp Business Journal, $130 million worth of products containing the cannabinoid were bought in the U.S. in 2016. And that figure is only set to rise in the years to come, the data analyst believes. Indeed, the source estimates that consumer sales of CBD goods will total an astounding $2.1 billion by 2020 – buoyed, perhaps, by claims that the usage of such products can help alleviate the symptoms of chronic pain, depression and diabetes, to name but a few conditions.
Kat’s Naturals not only takes the quality of its products seriously, but it also ensures that their contents are produced in a way that’s as environmentally friendly as possible. The essential oils in its best-selling Heal CBD Hemp Oil, for example, are harvested in a sustainable manner, while the hemp that goes into its range more generally is completely organically grown. And in a customer-friendly move, Kat’s Naturals provides CBD oil blends specifically tailored to users’ needs, whether they want to boost metabolism, get a good night’s rest or simply feel freer from muscle pain. Perhaps the most innovative Kat’s Naturals product, though, is its CBD-containing capsaicin cream. This topical owes its heat in part to a component commonly found within chili peppers, and the company’s website claims that it also helps give respite to neuropathy sufferers and those with Raynaud syndrome.

The CBD oil in everything that’s sold by Receptra Naturals is extracted from hemp from family-owned farms in Colorado. And the oil produced by the hemp plants – which are cultivated completely organically – is only taken from the flowering parts to ensure its purity and quality. Those of an environmentally conscious bent may therefore particularly appreciate the company’s offerings, which include CBD oil blends that aim either to boost users’ overall sense of health or, for people who are particularly physically active, to just give them a bit more pep in their steps. The most potent of these oils is, for the record, a 4,000 mg concentrate. But Receptra Naturals’ range also includes a topical cream, a skin-conditioning body butter and a CBD extract blend for pets that, the producer states, may help with anxiety, mobility and digestion in animals.


CBD (short for cannabidiol) is one of at least 113 chemical compounds known as cannabinoids found in the cannabis plant. The popularity of CBD oil products continues to increase as more consumers learn about the potential health benefits. Anxiety, depression, chronic pain, inflammation, and insomnia are just a few of the conditions cited by users who are successfully using CBD products.

The human body also produces cannabinoids, known as endocannabinoids, in a bodily system known as the endocannabinoid system (or ECS). The ECS promotes homeostasis by regulating a wide range of functions, including motor skills, mood, appetite, and sleep. As we age, our ECS produces fewer endocannabinoids; they may also decrease due to physical injury or disease. Replenishing depleted endocannabinoids with phytocannabinoids like CBD can help restore balance to the body.

Dr. Cohen has found that chronic conditions including autoimmune diseases and pain syndromes can be helped with a 6-mg under-the-tongue tincture (the fastest delivery system) or a 25-mg capsule taken twice a day. Dosages for topical products like lotions are especially hard to determine—there’s no clarity on how much CBD gets into the system through the skin.
Fab has rapidly become the leading “lifestyle” brand in the industry. They are very engaged with their customers in their online community, and they have the top customer loyalty program that we’ve seen. Their full spectrum CBD oil drops and topical cream are made from 100% organically grown Colorado hemp, producing a very high-quality product. And their zero THC gummies get high marks from customers for taste and effectiveness.
Well there you have it – my list for the top 20 best CBD oils for sale in 2019. Let me reiterate the fact that I don’t have a ton of personal experience with each and every one of these brands, but I’ve dedicated the last couple of years to compiling reliable reviews to help average customers like you steer away from low-quality products. These are the companies I believe to be the best ones currently out there – at least as far as legal CBD for sale online. Honestly, it’s not easy finding the perfect tincture, and figuring out the best CBD oil for you personally will require some patience, due diligence, and a keen ability to listen to your body. If you have the energy and can dish out the time and effort though, I truly feel that you’ll be more than happy with the therapeutic potential of hemp-based CBD.
DISCLOSURE: The statements made regarding these products have not been evaluated by the Food and Drug Administration. The efficacy of these products has not been confirmed by FDA-approved research. These products are not intended to diagnose, treat, cure or prevent any disease. All information presented here is not meant as a substitute for or alternative to information from health care practitioners. Please consult your health care professional about potential interactions or other possible complications before using any product.
The main reason we like Kat’s Naturals CBD oils are because they use hempseed oil to infuse 1,500 mg of CBD isolate. While the hempseed itself doesn’t contain any actual CBD, it is chock-full of phytonutrients, plant protein, and other nutritious compounds. The only reason other companies use coconut or MCT oil to infuse the CBD instead of hempseed oil, is because hempseed is lower in saturated fat so it doesn’t have as great a bioavailability. In other words, taking a CBD oil infused in MCT oil will allow more of the active compound to reach parts of the body that you need it to. For combining the natural therapeutic elements of CBD with the nutritional benefits of hempseed, however, Kat’s Naturals is a great product. I would recommend using it as a daily health supplement moreso than an actual therapy to treat any kind of condition or ailment.
Along with PureKana and Premium Jane, MedTerra CBD is one of the few companies that has a commercialization agreement with hemp farms under the Kentucky Pilot Research Program. My partner and I really like this brand because it’s clear that they’re much more focused on health and science rather than creating gimmicky promotions and web advertisements to try and build their “brand.” The CBD industry definitely needs more companies with this mentality. We haven’t tried them a whole lot, but we did receive a couple of samples of their “Medoil Tinctures,” and they worked particularly well for my partner’s anxiety and sleep issues. They also were OK for my back pain, but not quite as potent as some other brands I’ve used.
If you are new to the world of CBD, it is definitely best for you to start with a lower dosage and work your way up from there. Some of the tinctures listed below have as few as 240mg of cannabidiol per bottle, while others are as high as 4850mg. While stronger isn’t always better, we appreciate those brands that have different options available to address different needs. Also, keep in mind that while a lower dose can give you more control over the amount you consume, a higher concentration is usually more cost effective. Higher concentrations will also contain more beneficial cannabinoids.
NuLeaf Naturals markets themselves as “the world’s premier CBD oil company” – I don’t know if I’d quite go to that extent and say that, but I will say that my partner Josh and I have both tried their full-spectrum tinctures, and they do work incredibly well. Also, they main reason they made it on my list here of the best CBD oils online is the fact they offer one of the most potent oral tinctures on the market: a 1,450 mg super highly concentrated oil that wiped my back pain out in less than 20 minutes. To be clear, that’s 45% more potent than PureKana’s strongest oil (1,000 mg). Why don’t I use NuLeaf Naturals all the time then, you might be wondering? Well, I can get away with much smaller doses than that, so there’s no reason to take such a potent dose if I don’t need to. If you’ve been scrounging around the web trying to find a super strong CBD oil, or have otherwise not had great results with other products, I definitely recommend trying some of NuLeaf Naturals’ stuff out. Be advised, though, that it ain’t cheap!
Another point worth clarifying is the difference between hemp seed oil (or hemp oil) and CBD oil. There’s confusion on this point for the very good reason that both CBD oil and hemp seed oil are extracted from the industrial hemp plant. But there’s a big difference between the 2. Hemp seed oil has been pressed from hemp seed, and it’s great for a lot of things — it’s good for you, tastes great, and can be used in soap, paint — even as biodiesel fuel. 
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