The endocannabinoid system is spread throughout your brain and body, but primarily throughout your central nervous system. The interaction between cannabinoids and receptors is what produces effects like the regulation of mood, pain, appetite, inflammation, and memory. Plant-based cannabinoids, found in cannabis plants, also interact with the receptors (whimsically named CB1 and CB2) in the endocannabinoid system, and each affects your body in different ways. CBD and its infamous cousin THC are the 2 most well-known cannabinoids.
CBD (Cannabidiol) is a potent, non-psychoactive cannabinoid found in hemp oil. It is typically extracted from industrial hemp plants that are naturally high in CBD and other phytochemicals. It is the most prevalent of over 80 different cannabinoids found in natural hemp. It is commonly used for its therapeutic properties. Cannabidiol is responsible for a wide-range of positive health benefits through its interaction with the body's own endocannabinoid system.
We suggest using our dosage calculator to find the right dose or amount of CBD for your needs. If you are looking for relief for a specific issue, for example, back pain we suggest starting with our CBD Quiz to find the right product for you needs. Also if a organic or Non-GMO product is important for you look for that on the label or in the product description. Lastly, understand if you would prefer a full-spectrum cbd oil or a CBD isolate.  A full-spectrum oil contains many other beneficial parts of the hemp/cannabis plant while an isolate removes everything except CBD. Learn more about the difference here here.
Transparency: Receptra Naturals’ website has a database where you can look up lab reports for their products. The first time we checked, we got some 404 errors for a couple of the lab reports, but these glitches seem to have been fixed since then. We were able to see third-party lab reports for all their tinctures (though, apparently not for their topicals). 
The human body also produces cannabinoids, known as endocannabinoids, in a bodily system known as the endocannabinoid system (or ECS). The ECS promotes homeostasis by regulating a wide range of functions, including motor skills, mood, appetite, and sleep. As we age, our ECS produces fewer endocannabinoids; they may also decrease due to physical injury or disease. Replenishing depleted endocannabinoids with phytocannabinoids like CBD can help restore balance to the body.
Unlike THC, CBD will not make you high. That said, this doesn’t mean CBD is not at all psychoactive, as many assert, says Jahan Marcu, PhD, director of experimental pharmacology and behavior at the International Research Center on Cannabis and Mental Health in New York City: “CBD does change cognition. It affects mood, which is why people take it for anxiety. And some find that it makes them more alert.”
Terpenes are the naturally-occurring essential oils from plants, flowers, and vegetables. Terpenes are what give the plant its scent, flavor, and unique benefits. Some of the terpenes in cannabis are known for their useful therapeutic properties. For example, some terpenes are known for their anti-inflammatory, anti-anxiety, or relaxing properties to name a few.

Dr. Cohen has found that chronic conditions including autoimmune diseases and pain syndromes can be helped with a 6-mg under-the-tongue tincture (the fastest delivery system) or a 25-mg capsule taken twice a day. Dosages for topical products like lotions are especially hard to determine—there’s no clarity on how much CBD gets into the system through the skin.


They operate their own hemp farms in Kentucky and Colorado as well as their own lab and product facilities. Customers appreciate their dedication to making quality products at affordable prices. It’s also great to see a company that’s willing to stand behind their products by offering a 30-day money-back guarantee if you’re dissatisfied for any reason.
People taking other medications: When side effects are reported, it’s often by this group. CBD appears to have a similar effect to grapefruit on the liver’s ability to metabolize certain drugs, which can lead to adverse side effects. Generally, if a medication has a grapefruit warning, you should avoid taking CBD. Although, if you are on any medication you should talk to your doctor before starting CBD, to ensure you won’t expect any negative interactions.
Secondly, all products are NOT created equal – they differ significantly in strength, absorption, and elimination by the body and in the manner in which they are formulated. One should be mindful of the differences in doses available for each of these products, starting at a low or moderate dose and increasing as needed in order to find the lowest dose that provides the desired relief. In this way, one can individualize usage to maximize effectiveness while minimizing risk – a proper goal for the use of all medicinals.

Other CBD oil stores have high-quality products, but our choice came down to variety, potency, and price. Whichever you choose to go for, though, know that all of the companies above have an outstanding store and offer a wide range of effective products, from CBD oils to Terps and even CBD creams. Plus, most have a 100% money-back guarantee policy, which is quite nice!
The average person sleeps around 480 minutes each day, that is unless you are one of the 70 million Americans who suffer from one of several sleep disorders. With so many Americans suffering from sleep problems and low sleep quality, it’s not surprising that many sleepers are turning to the sedating effects of CBD to get a good-nights sleep. When suffering from insomnia, your first thought may be to purchase an over-the-counter supplement such as melatonin from your local pharmacy, but let us explain why CBD may be a better choice for your sleep aid needs. 
Infinite CBD specializes in CBD isolate, meaning CBD oils that are not full-spectrum and do not contain the full range of hemp extract. As such, I have hardly used them at all because I generally always prefer full-spectrum CBD tinctures. That being said, if you’re looking for isolate I would venture to say that Infinite CBD is the best CBD isolate oil on the market right now, hands down. If you need to avoid full-spectrum oils for drug testing purposes, definitely give them a try.

The main reason we like Kat’s Naturals CBD oils are because they use hempseed oil to infuse 1,500 mg of CBD isolate. While the hempseed itself doesn’t contain any actual CBD, it is chock-full of phytonutrients, plant protein, and other nutritious compounds. The only reason other companies use coconut or MCT oil to infuse the CBD instead of hempseed oil, is because hempseed is lower in saturated fat so it doesn’t have as great a bioavailability. In other words, taking a CBD oil infused in MCT oil will allow more of the active compound to reach parts of the body that you need it to. For combining the natural therapeutic elements of CBD with the nutritional benefits of hempseed, however, Kat’s Naturals is a great product. I would recommend using it as a daily health supplement moreso than an actual therapy to treat any kind of condition or ailment.

“Buying from a reputable manufacturer is crucial, because it matters how the plant is cultivated and processed,” Dr. Maroon says. One clue that a company is cutting corners: too low a cost. Good CBD is pricey—a bottle of high-quality capsules is sold in Cohen’s office for $140. But for many, it’s worth the money. Roth spent $60 on her tiny bottle. But when her energy returned the day she started taking CBD, she decided that was a small price to pay.

It’s fair to say that the CBD market is thriving. According to market intelligence company Hemp Business Journal, $130 million worth of products containing the cannabinoid were bought in the U.S. in 2016. And that figure is only set to rise in the years to come, the data analyst believes. Indeed, the source estimates that consumer sales of CBD goods will total an astounding $2.1 billion by 2020 – buoyed, perhaps, by claims that the usage of such products can help alleviate the symptoms of chronic pain, depression and diabetes, to name but a few conditions.
Hemp Bombs is based in Tampa, Florida, and in addition to focusing on the purity and therapeutic effectiveness of their products, are dedicated to establishing themselves as a top brand in the industry with a specific target audience. One of our personal favorite products of theirs is the flavored CBD vape liquids, which are some of the best-tasting CBD vape juices we’ve ever had.
CBD Fx is another USA company that emphasizes the use of MCT oil for maximizing the bioavailability of the CBD compound to cells throughout the body. In layman’s terms, this basically means their goal is to create a highly efficient and effective tincture that bypasses metabolic breakdown processes in the digestive system. They’re also big into vape pens, CBD vaping and CBD concentrates (waxes, powders, crystal isolates etc), so they tend to appeal a lot to the younger population as well as older folks like me who need CBD oil basically just to get out of bed in the morning.    

CBD products have seen a huge rise in popularity over the past four years, beginning when the Agricultural Act of 2014 allowed the growth of industrial hemp. CBD oil has gained serious traction in the alternative medicine market, where it is reported to help with sleep disorders, migraines, pain relief (especially neck pain), anxiety, and even epilepsy. Because it contains 0–.3% THC (the psychoactive cannabinoid in marijuana), CBD appeals to a wide range of people, including those who would not have used medical marijuana due to the head high they would experience.
Drops (also referred to as tinctures) are the most popular way to take CBD oil. They are typically sold in glass bottles with a built-in dropper. The drops are placed under your tongue and held there for at least 60 seconds. This drop process allows the CBD to absorb sublingually into your bloodstream. Other popular ways to take CBD include vaping, gummies, capsules, and topical creams. How you take it is a personal decision based on your preferences. Many experienced users take multiple different products at the same time.
The CBDistillery has two main strengths. The first is its variety of options. The CBDistillery offers CBD oil tinctures in a wide range of concentrations from 17mg up to 88 mg of CBD per serving. But what really sets the company apart is that they offer both full-spectrum and THC-free CBD oil options. Most people gravitate towards full-spectrum CBD oil to take advantage of the entourage effect. But with THC-free CBD oil, you can enjoy the benefits and effects of CBD even if you’re subject to mandatory drug testing.
Brian Peterson has been a CBD consumer advocate and educator since 2013. He is the founder and managing editor of the CBDOilUsers.com website. He's also the lead administrator of the CBD Oil Users Group, the largest CBD group on Facebook. His passion is educating consumers so that they can make their own decisions when purchasing and using CBD products.
Los Angeles-based PureKana stresses that it extracts the CBD oil for its products from hemp plants that have been cultivated without the use of herbicides, pesticides or other agro-industrial chemicals that may impact upon crops. What’s more, the company states, no solvents go into the extraction process other than carbon dioxide. And to further put potential customers’ minds at rest, PureKana presents the results of third-party testing of its CBD oil tincture on its website – a welcome nod to transparency. That tincture can be found in the company’s own blend of CBD oil drops – the three varieties of which have elicited highly complimentary reviews from users – as well as its capsules and cooling topical ointment. Meanwhile, for anyone with a sweet tooth, PureKana’s CBD isolate-containing gummy bears may just do the trick.

Technically speaking, its THC—the cannabinoid that gets you high—which is illicit. When you take a drug test, the aim is to detect THC in your body, not “cannabis.” If you possessed weed without any THC in it, technically you wouldn’t be in violation of the law. Because “weed” without THC has a different name: hemp. And the rules governing hemp are quite different from the restrictions placed on cannabis.


Owned by CV Sciences, PlusCBD Oil applies experience from the pharmaceutical industry to CBD. The company’s mission: optimize human health with the endless potential of hemp. Using state of the art production facilities and the guidance of a scientific advisory board, PlusCBD Oil is another high-quality purveyor of CBD oil that really takes CBD seriously.
CBD American Shaman’s extensive array of products ought to satisfy even the pickiest customer, ranging as it does from flavored tinctures to CBD-infused under-eye serum – and even, for horse lovers, an “equine ointment.” Furthermore, its inventive, water-soluble hemp oil supplement means that users can get their daily dose of CBD just by quenching their thirst. They’re all ways through which CBD American Shaman, as the website states, aims to “[bring] wellness to the world.” The company has a philanthropic streak, too, with a pledge that it frequently gives to non-profit organizations, while its “Compassionate Care” scheme cuts the prices of its goods for those with long-term health conditions. Plus, the company asserts that it uses only organic, non-genetically modified hemp in the making of its CBD oil products, with no insecticides used in the growing process.
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