Not all CBD is created equally. Some tinctures are created with little regard to overall consumer safety, and may contain harmful chemicals and pesticides. Other CBD products have been shown to differ from what the label says, either with way more cannabidiol, or way less. In some cases, the THC content was elevated above the federal legal limit for hemp extracts.
Water soluble CBD oil products are formulated using a special process to break down the CBD molecules into smaller particles. In theory, “water compatability” would produce higher absorption rates and faster-acting effects. Although it’s a popular buzzword in the CBD industry, we have yet to see any independent research studies that prove they are better than traditional oil-based tinctures.
This is a confusing one for many people. "A lot of brands don't do a good job of clearly instructing their consumer on the dosing," says Chris Roth, CEO and co-founder of Highline Wellness. When thinking about dosing, also consider whether your CBD is full-spectrum or isolate: Full-spectrum could include other cannabinoids like cannabidivarin or cannabigerol (this is important, since "there's something called the 'entourage effect' when all together, they're more effective than any one of them alone," Roth explains), while isolate is 100% CBD. "Some people might only need 10 milligrams of full-spectrum CBD, but with isolate, even taking 80 or 100 milligrams might not have the same effect," he says.
CBDistillery is our Editor’s Pick because of its diverse product line and commitment to high quality and customer service. They’ve earned a rating of 9.7/10 from our users who most often mention their product quality, effectiveness, great prices, and fast shipping times. Their most popular product is their 1000mg 30ml full spectrum CBD oil tincture. Priced at $60, it has 33mg of CBD per milliliter and is an excellent starting point for beginners. In addition to other full spectrum options, they also have zero THC drops for those looking for CBD oil without THC.
In addition to acting on the brain, CBD influences many body processes. That’s due to the endocannabinoid system (ECS), which was discovered in the 1990s, after scientists started investigating why pot produces a high. Although much less well-known than the cardiovascular, reproductive, and respiratory systems, the ECS is critical. “The ECS helps us eat, sleep, relax, forget what we don’t need to remember, and protect our bodies from harm,” Marcu says. There are more ECS receptors in the brain than there are for opioids or serotonin, plus others in the intestines, liver, pancreas, ovaries, bone cells, and elsewhere.
CBD has proven neuroprotective effects and its anti-cancer properties are being investigated at several academic research centers in the United States and elsewhere. A 2010 brain cancer study by California scientists found that CBD “enhances the inhibitory effects of THC on human glioblastoma cell proliferation and survival.” This means that CBD makes THC even more potent as an anticancer substance. Also in 2010, German researchers reported that CBD stimulates neurogenesis, the growth of new brain cells, in adult mammals.
*[A couple things of note before I begin the reviews. In order to avoid redundancy and limit repeating myself dozens of times over, be advised that (unless otherwise noted), all of the companies listed below employ standard practices that are used by all of the best CBD oil companies, including things like: solventless CO2 extraction, 3rd party laboratory testing, legal THC limits below 0.3%, shipping to all 50 U.S. states, etc..]
The growth of CBD Pure within the last several months has been somewhat surprising given their little-known status the first time I tried them last year. They’re not quite as potent and long-lasting as something like Premium Jane or PureKana, but like CBD Essence they’ve mostly made it this high up on the list due to their affordable prices. Believe it or not, in fact, they’re nearly 60% cheaper than PureKana on an oz-to-oz basis. If you’re just trying out CBD for the first time and want to see how it works for you before jumping to one of the more expensive brands, I’d definitely take a look at CBD Pure’s range of affordable tinctures.

People taking other medications: When side effects are reported, it’s often by this group. CBD appears to have a similar effect to grapefruit on the liver’s ability to metabolize certain drugs, which can lead to adverse side effects. Generally, if a medication has a grapefruit warning, you should avoid taking CBD. Although, if you are on any medication you should talk to your doctor before starting CBD, to ensure you won’t expect any negative interactions.


This is why Amanda Oliver, 31, a career consultant in Charleston, SC, pops a CBD gummy bear each night before bed. “I used to lie there tossing and turning as my mind raced from work projects to whether I had set the home alarm,” Oliver says. One piece of candy with 15 milligrams (mg) of CBD is enough to shut off her brain and facilitate sleep. She also swears by the CBD oil she takes at the height of her period, which she says quells her debilitating cramps.
The reason so many people are interested in cannabis products that don’t make them high, proponents say, is that CBD helps with everything from pain and nausea to rheumatoid arthritis, cancer, Crohn’s disease, and dementia. CBD is anti-inflammatory, anti-anxiety, antibacterial, immunosuppressive, and more, says Joseph Cohen, DO, a cannabis doctor in Boulder, CO.
CBD American Shaman’s extensive array of products ought to satisfy even the pickiest customer, ranging as it does from flavored tinctures to CBD-infused under-eye serum – and even, for horse lovers, an “equine ointment.” Furthermore, its inventive, water-soluble hemp oil supplement means that users can get their daily dose of CBD just by quenching their thirst. They’re all ways through which CBD American Shaman, as the website states, aims to “[bring] wellness to the world.” The company has a philanthropic streak, too, with a pledge that it frequently gives to non-profit organizations, while its “Compassionate Care” scheme cuts the prices of its goods for those with long-term health conditions. Plus, the company asserts that it uses only organic, non-genetically modified hemp in the making of its CBD oil products, with no insecticides used in the growing process.

The CBD oil in everything that’s sold by Receptra Naturals is extracted from hemp from family-owned farms in Colorado. And the oil produced by the hemp plants – which are cultivated completely organically – is only taken from the flowering parts to ensure its purity and quality. Those of an environmentally conscious bent may therefore particularly appreciate the company’s offerings, which include CBD oil blends that aim either to boost users’ overall sense of health or, for people who are particularly physically active, to just give them a bit more pep in their steps. The most potent of these oils is, for the record, a 4,000 mg concentrate. But Receptra Naturals’ range also includes a topical cream, a skin-conditioning body butter and a CBD extract blend for pets that, the producer states, may help with anxiety, mobility and digestion in animals.
Being more a traditional gal, it’s kind of funny that I like Hemp Bombs CBD so much. Judging by their Instagram and so forth it seems like they’ve made an effort to appeal to a younger, more “hip” crowd, but I don’t care – they sell some darn good CBD products and that’s the only thing that matters to me. And actually, if you’re into vaping CBD oil or prefer to use a CBD vape pen, they’re definitely the company that I would recommend the most. I’m not huge into vaping myself, but they’ve got a MASSIVE range of high-quality (and highly potent) CBD vape products in addition to the standard stuff like oral tinctures and CBD capsules. My partner has even used the “Sugar Cookie Kryptonite” vape liquid and absolutely loved it! Really, you’ve got to just spend some time browsing their store to come to terms with the huge range of products they’ve got: CBD “Pain Freeze,” CBD “Max Chill Shots,” and even a brand new product called CBD Beard Oil!!
PlusCBD Oil offers three different CBD oil formulations. The Total Plant Complex formulation is unflavored and made with extra virgin olive oil. It also has the fewest additives of all of their oils and contains 4 mg of CBD per serving. The Gold Formula comes in unflavored, goji berry, and peppermint flavors with options for 3 mg, 5 mg, or 9 mg of CBD per serving. And the Raw Formula is available in 1mg and 3mg concentrations. It’s high in CBDA which has unique therapeutic properties distinct from CBD.
CBD oil users looking for a product that packs a punch could do well by picking up The CBDistillery’s 5,000 mg full-spectrum tincture – the most potent of the company’s range. Customers wanting a slightly gentler CBD hit, however, can opt instead for one of the provider’s vape oil pens or its 25 mg capsules. And for people who prefer to get their daily CBD dose through dabbing, The CBDistillery offers an array of flavored terpsolates, too, as well as a user-friendly walk-through of the process of dabbing for the uninitiated – a guide in keeping with the brand’s desire to “[spread knowledge] about CBD to the masses.” Added to which, The CBDistillery keeps prices lower for veterans and those currently serving in the armed forces by providing a 10-percent discount on any purchases made.
There are many scammers and multi-level marketing salespeople that use Facebook and other social media outlets to push a particular product. Many of them will tell you whatever you want to hear to get you to buy from them. Be wary of their claims and testimonials. It’s particularly important to buy CBD oil from a brand that makes third party lab reports readily available. This third party certification is the only way for you to truly know what is in the product.
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