There are many scammers and multi-level marketing salespeople that use Facebook and other social media outlets to push a particular product. Many of them will tell you whatever you want to hear to get you to buy from them. Be wary of their claims and testimonials. It’s particularly important to buy CBD oil from a brand that makes third party lab reports readily available. This third party certification is the only way for you to truly know what is in the product.

This means high doses of CBD could significantly decrease the metabolization of cocaine. In fact, a study done on mice found exactly that 11. But what they also found was that CBD only significantly decreased the metabolization of CYP substrates like cocaine, when taken in extremely high doses off 30mg/kg. Such a high CBD dose far surpasses the currently maximum recommended dose of 1500mg/day.

Transdermal Patches – Remember those patches people put on their bodies to quit smoking? These patches allowed for a slow release of nicotine over the course of a day? Well, the same idea exists with CBD patches. This is a convenient way to get CBD into your body and endocannabinoid system over the course of a day. CLICK HERE to see our favorite patch.


CBD oil products needn’t be expensive, as Canabidol proves. The company’s pure cannabis oil drops, for example, sell from $28 for 10 ml, making them an affordable choice for new users still unsure about what CBD could do for them. That’s not to say that Canabidol’s goods aren’t up to scratch, though, as the business aims to ensure their quality through both its own bespoke method of analysis and by sending its oil to third-party labs. Among the products on offer, meanwhile, are innovative CBD Gel-Tabs, which feature a specially developed slow-release system designed to improve the body’s absorption of the active ingredient. And this, Canabidol claims, is “now the best-selling CBD cannabis oil product in the U.K.”

In addition to acting on the brain, CBD influences many body processes. That’s due to the endocannabinoid system (ECS), which was discovered in the 1990s, after scientists started investigating why pot produces a high. Although much less well-known than the cardiovascular, reproductive, and respiratory systems, the ECS is critical. “The ECS helps us eat, sleep, relax, forget what we don’t need to remember, and protect our bodies from harm,” Marcu says. There are more ECS receptors in the brain than there are for opioids or serotonin, plus others in the intestines, liver, pancreas, ovaries, bone cells, and elsewhere. 

Koi CBD probably should be higher up on this list given their popularity, but since they’re geared more towards vaping and CBD vape oils, and I have never really used them too much. People who do use them everyday though say that they’ve got the best flavors of any CBD vape oil on the market, and I can say personally that their CBD gummies and spearmint CBD oil work decently as well. I would recommend Koi CBD if you’re big into vaping and have yet to find a CBD vape oil that you like, and/or if you’re looking for a reputable brand that sells high quality oral CBD tinctures as well as edibles and vape products – might as well order everything in one place.
CBD Essence is another brand we’ve had plenty of experience with over the past 18 months or so, and my partner particularly likes his 600 mg Medicinal Grade tincture for quickly easing her anxiety. I haven’t tried them so much for may pain, but I do recall that a 30 mg dose was quite effective the last time I did take it. Also, the main reason they’re this high up on our list is because they’re a fair amount cheaper than Elixinol and PureKana. Their tinctures come in larger 2 oz bottles, but on a CBD-per-mg basis they’re about 20% less expensive than other top-quality brands.
Medterra prides itself on offering what it terms “true seed-to-sale purchases,” with the hemp crop used for its CBD oil cultivated and extracted to the exacting standards demanded by the Kentucky Department of Agriculture. Potential buyers may be encouraged, too, to know that “quality, consistency and safety are… top priorities” at Medterra, and to that end all of the raw materials the company uses are independently lab tested. Plus, those who decide to take the plunge and order from the provider’s site can reap the benefits of its rewards program, with points given for Facebook shares, reviews and purchases. Among the products on offer at Medterra are CBD oil tinctures, capsules and pain-alleviating cream, all of which fall under a money-back pledge if not deemed to be to customers’ satisfaction.
CBD derived from marijuana is a different story, and the law varies from state to state. But as long as you’re using CBD oil that contains less than 0.3 percent THC, you have nothing to be concerned about anywhere in the United States. On the other hand, if you want to take your CBD on a trip outside the country, definitely look into local laws to avoid getting into awkward situations while you’re away.

Owned by CV Sciences, PlusCBD Oil applies experience from the pharmaceutical industry to CBD. The company’s mission: optimize human health with the endless potential of hemp. Using state of the art production facilities and the guidance of a scientific advisory board, PlusCBD Oil is another high-quality purveyor of CBD oil that really takes CBD seriously.


Through its regularly updated and highly informative blog, Koi CBD goes the extra mile to help its customers learn about new developments in the field of CBD use. The company also helps its patrons out by publishing full lab results on each of its products, helping CBD oil users know exactly what to expect. And those purchases may include Koi’s bespoke full-spectrum CBD oil blend, complete with fellow cannabinoids CBDV, CBN and CBG – the inclusion of which, the company claims, “provide[s] the ultimate experience in CBD.” Also available to buy from Koi’s website are a range of 1,000 mg vaping liquids, lavender-scented body lotion, tropical-flavored gummies and, for canine CBD lovers, chewable treats.
Children: Like pregnant and breastfeeding women, clinical research among child-aged participants is less common. To date, much of the research of CBD with children has involved children with severe pediatric epilepsy. This research found CBD oil to be effective in symptom management, leading to the first FDA-approved drug containing CBD. However, the efficacy and safety of CBD for children has not been studied sufficiently to know if it has any long-term effects.
After two decades of experience in the hemp industry, Paul Benhaim founded Elixinol – ostensibly, as the company’s website states, to “[manufacture] and [provide] the highest-quality CBD oil and hemp extracts in the world.” And so that CBD oil users can be assured of that quality, Elixinol extensively tests its extracts and provides certificates of analysis for its products that are available to view at a click. The manufacturer’s wares have even received a “stamp of approval” from The Realm of Caring Foundation, a Colorado-based non-profit and advocate for cannabinoid therapy research and education. Those wanting to assess Elixinol’s extracts for themselves can choose from its range of oral tinctures – with potencies of 300 mg, 600 mg and 3,600 mg – as well as topical balms and capsules. Plus, the company gives 5 percent of the proceeds from every sale to charity – so buyers may not only feel good after their purchases, but they’ll do some good, too.
PlusCBD Oil is one of the few companies that doesn’t source their hemp from the United States. Although the company is working to move its hemp farming to the United States, PlusCBD Oil currently imports hemp grown in Europe. But don’t let that worry you. PlusCBD Oil is still certified by the U.S. Hemp Authority, meaning they follow high standards, industry best practices, and self-regulation.
NuLeaf Naturals markets themselves as “the world’s premier CBD oil company” – I don’t know if I’d quite go to that extent and say that, but I will say that my partner Josh and I have both tried their full-spectrum tinctures, and they do work incredibly well. Also, they main reason they made it on my list here of the best CBD oils online is the fact they offer one of the most potent oral tinctures on the market: a 1,450 mg super highly concentrated oil that wiped my back pain out in less than 20 minutes. To be clear, that’s 45% more potent than PureKana’s strongest oil (1,000 mg). Why don’t I use NuLeaf Naturals all the time then, you might be wondering? Well, I can get away with much smaller doses than that, so there’s no reason to take such a potent dose if I don’t need to. If you’ve been scrounging around the web trying to find a super strong CBD oil, or have otherwise not had great results with other products, I definitely recommend trying some of NuLeaf Naturals’ stuff out. Be advised, though, that it ain’t cheap!
Sadly, there are unscrupulous companies out there looking to take advantage of people wanting to try CBD oil. A free trial bottle of CBD oil sounds like a great deal. They say you just need to pay a small shipping and handling fee. But what really happens is that they will send you a very low quality product. They’ll also keep charging your credit card every month for as much as $90 per month until you cancel your “subscription” with them. This is an outright scam that you want to avoid.
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